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Dr. LAKSHAY MALHOTRA

Dr. LAKSHAY MALHOTRA

ASSISTANT PROFESSOR

BIO-CHEMISTRY

Emaillakshayaiims@gmail.com
Educational Qualifications
Degree / CertificationInstitutionYear
Ph.D.All India Institute of Medical Sciences (AIIMS), New Delhi2023
M.Sc. Medical BiotechnologyAll India Institute of Medical Sciences (AIIMS), New Delhi2019
B.Sc (H) BiochemistrySri Venkateswara College, University of Delhi, India2017
Career Profile & Administrative Assignments
CategoryRole / DesignationDept / InstitutionPeriodRemarksAttachment
ADMINISTRATIVE ASSIGNMENTS MEMBER GURUKUL Sri Venkateswara College 11.Aug.2025 – Till date
ADMINISTRATIVE ASSIGNMENTS MEMBER RESEARCH COMMITTEE OF THE COLLEGE (RCC) Sri Venkateswara College 11.Aug.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS MEMBER SUBJECT RESEARCH COMMITTEE Sri Venkateswara College 11.Aug.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS MEMBER NAAC CRITERION 2 Sri Venkateswara College 27.Jul.2025 – Till date
ADMINISTRATIVE ASSIGNMENTS MEMBER LIBRARY COMMITTEE Sri Venkateswara College 01.Jul.2025 – Till date
CAREER PROFILE MEMBER DEPARTMENT MODERATION COMMITTEE (DMC) Sri Venkateswara College 01.Jul.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS TEACHER-IN-CHARGE DEPARTMENT OF BIOCHEMISTRY Sri Venkateswara College 01.Jun.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS DEPARTMENT CORDINATOR:IQAC DEPARTMENT OF BIOCHEMISTRY Sri Venkateswara College 01.Jun.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS MEMBER SVC PRACTICAL EXAMINATION Sri Venkateswara College 01.Jun.2025 – 31.May.2026
ADMINISTRATIVE ASSIGNMENTS MEMBER OTHERS Sri Venkateswara College 27.Jan.2025 – 30.Jun.2025 Member of “SVC गुरुकुल: विद्यालय से महाविद्यालय तक team
ADMINISTRATIVE ASSIGNMENTS MEMBER OTHERS Sri Venkateswara College 08.Oct.2024 – 30.Jun.2025 DATA (Data Acquisition team for Alumni)
ADMINISTRATIVE ASSIGNMENTS MEMBER PLACEMENT CELL Sri Venkateswara College 30.Jul.2024 – 01.Jun.2025
ADMINISTRATIVE ASSIGNMENTS DEPARTMENT CO-COORDINATOR:IQAC DEPARTMENT OF BIOCHEMISTRY Sri Venkateswara College 18.Jul.2024 – 30.Jun.2025
ADMINISTRATIVE ASSIGNMENTS CO-COORDINATOR NAAC CRITERION 2 Sri Venkateswara College 08.Jul.2024 – Till date
ADMINISTRATIVE ASSIGNMENTS CONVENER BIOLOGICAL SCIENCES - CHRYSALIS Sri Venkateswara College 01.Jul.2024 – 30.Jun.2025
ADMINISTRATIVE ASSIGNMENTS MEMBER LIBRARY COMMITTEE Sri Venkateswara College 01.Jul.2024 – Till date
Other Profiles & Specializations
AWARDS AND DISTINCTIONS

1. Dr. S.V. Talekar Medal-2023 (Gold Medal) for Best Postgraduate (Ph.D.) from the Department of Biophysics, All India Institute of Medical Sciences (AIIMS), New Delhi

2. DBT - Senior Research Fellowship (2021-2023)

3. DBT - Junior Research Fellowship (2019-2021)

4. CSIR JRF and LS (July 2018)

5. CSIR JRF and LS (Jan 2018)

Research Guidance

No research guidance entries published.

Publications
CategoryJournal / ConferenceTitleAuthor(s)Month / YearAttachment
JOURNAL PAPER
International
Metronomic Chemotherapy in Ovarian Cancer: Current Scenario and AI-Integrated Future Strategies Cancer Reports Ravi Chauhan, Suraja Kumar Das, Lakshay Malhotra et al.
Joint Author
July 2026
JOURNAL PAPER
International
The multifaceted nature of mollusk shell proteins: a complex interplayof protein sequence, function, and biomineralization Journal of Biomolecular Structure and Dynamics Pratibha Sharma, Lakshay Malhotra, Rajinder K. Dhamija, Alagiri Srinivasan
Joint Author
June 2026
JOURNAL PAPER
International
Hypoxia-Induced Metabolic and Apoptotic Reprogramming Enhances Immunomodulation in Wharton’s Jelly Mesenchymal Stem Cells iScience Mohini Mendiratta, Meenakshi Mendiratta, Sujata Mohanty, Hridayesh Prakash, Lakshay Malhotra et al.
Joint Author
March 2026
JOURNAL PAPER
National
IGFBP3 repression driven by inflammation links air pollution to placental and developmental defects EMBO Molecular Medicine Sunil Singh; Isha Goel; Anubhuti Rana; Javed. A Quadri; Asit R. Mridha; Lakshay Malhotra et al.
Joint Author
March 2026
JOURNAL PAPER
International
Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-4 Journal of Translational Medicine Ravi Chauhan, Gunjan Dagar, Lakshay Malhotra, et al.
Joint Author
December 2025
CONFERENCE PAPER/ PROCEEDINGS
International
Development of a novel anti BCMA (B cell Maturation Antigen) 9C4 academic CAR as a low cost adaptive cellular therapy candidate in multiple myeloma 2630 The Journal of Immunology Mayank Singh , Ashna Gupta , Gunjan Dagar , Lakshay Malhotra , Kalpana Luthra , Ranjit Kumar Sahoo
Joint Author
November 2025
CONFERENCE PAPER/ PROCEEDINGS
International
Development of a novel economical anti-BCMA antibody for targeted therapeutic intervention in multiple myeloma Journal of Immunotherapy for Cancer Ashna Gupta, Gunjan Dagar, Lakshay Malhotra, Ravi Chauhan, Kalpana Luthra, Mayank Singh
Joint Author
November 2025
CONFERENCE PAPER/ PROCEEDINGS
International
Ubiquitin specific peptidase 14 (USP-14) mediate oncogenesis in Cervical cancer by interacting and modulating activity of Monocarboxylate transporter 4 (MCT-4) Cancer Research Ravi Chauhan; Lakshay Malhotra; Ashna Gupta; Gunjan Dagar; Ethayathulla Abdul Samath; Mayank Singh
Joint Author
August 2025
JOURNAL PAPER
International
Biophysical and molecular characterization of HuR inhibitors, CMLD-2 and Dihydrotanshinone I (DHTS), in Triple Negative Breast Cancer (TNBC) Internation Journal of Biological Macromolecules Arundhathi J.R. Dev, Lakshay Malhotra, Akanksha Kashyap, Sheikh Mohammad Umar, Meetu Rathee, Swarnava Samanta, Rahul Kharkwal, Debarka Sengupta, Chandra Prakash Prasad
Corresponding Author
July 2025
JOURNAL PAPER
International
Unraveling the unique amyloid-like aggregation behavior of the tumor suppressor p53 mutants in human cancers International Journal of Biological Macromolecules Nisha Manav, Pratibha Sharma, Sankat Mochan, Lakshay Malhotra
First Author, Corresponding Author
May 2025
CONFERENCE PAPER/ PROCEEDINGS
International
Exploring the therapeutic potential of USP14 in cervical cancer: mechanisms of oncogenesis and metabolic regulation Cancer Research Ravi Chauhan; Lakshay Malhotra; Ashna Gupta; Gunjan Dagar; Harshul Kapoor; Sandeep R. Mathur; Ethayathulla Abdul Samath; Mayank Singh
Joint Author
April 2025
CONFERENCE PAPER/ PROCEEDINGS
International
Ubiquitin specific peptidase 37 facilitate prostate cancer oncogenesis by regulation replication stress Cancer Research Gunjan Dagar; Asha Khuswaha; Lakshay Malhotra; Ashna Gupta; Ajaz Bhat; Ammira S Al-Shabeeb Akil; Atul Batra; Seema Khausal; Mayank Singh
Joint Author
April 2025
JOURNAL PAPER
International
The R337C mutation in the p53 oligomerization domain affects the regulatory domain and its ability to bind response elements: Evidence based on structural and biophysical studies Archives of Biochemistry and Biophysics Alankrita Singh, Lakshay Malhotra, Abhay Mishra, Simran Kundral, Pawan Kumar Tiwari, Saroj Kumar, Hariprasad Gururao, Punit Kaur, Abdul Samath Ethayathulla
Joint Author
March 2025
JOURNAL PAPER
International
Phenotypical mapping of TP53 unique missense mutations spectrum in human cancers Journal of Biomolecular Structure and Dynamics Lakshay Malhotra, Alankrita Singh, Punit Kaur & Abdul S. Ethayathulla
First Author
December 2024
JOURNAL PAPER
International
Elevated Serum sFlt-1 In Preeclamptic Mothers Activates GRP78 In Placenta African Journal of Biomedical Research Sankat Mochan, Chandan Kumar, Rinke Choudhary , Vishnu Swarup, Lakshay Malhotra, Mohd Anas Khan, Pallavi Arora, Renu Dhingra
Joint Author
November 2024
JOURNAL PAPER
International
Bergenin inhibits growth of human cervical cancer cells by decreasing Galectin-3 and MMP-9 expression Scientific Reports Ravi Chauhan, Lakshay Malhotra, Ashna Gupta, Gunjan Dagar, Mohini Mendiratta, Tariq Masoodi, Sheema Hashem, Sara Al Marzooqi, Dayasagar Das, Shahab Uddin, Abdul Samath Ethayathulla, et al.
Joint Author
July 2024
CONFERENCE PAPER/ PROCEEDINGS
International
Decoding the interplay of deubiquitinating enzymes (DUBs) in metastasis and chemoresistance of gynaecological cancers ESMO open R. Chauhan ∙ A. Gupta∙ G. Dagar∙ L. Malhotra∙ S. De∙ E.A. Samath∙ N. Singh∙ M. Singh
Joint Author
March 2024
CONFERENCE PAPER/ PROCEEDINGS
International
Unraveling the oncogenic network of USP37 and USP14 in gynecological cancers: Decrypting the molecular landscape of chemoresistance Cancer Research Ravi Chauhan; Ashna Gupta; Gunjan Dagar; Lakshay Malhotra; Ekta Rai; Muzafar A Macha; Ajaz A Bhat; Ethayathulla A Samath; Mayank Singh
Joint Author
March 2024
CONFERENCE PAPER/ PROCEEDINGS
International
Bergenin inhibits growth of human cervical cancer cells by decreasing galectin-3 and MMP-9 expression Cancer Research Mayank Singh; Ravi Chauhan; Lakshay Malhotra; Ashna Gupta; Gunjan Dagar; Dayasagar Das; Shahab Uddin; Ethayathulla Abdul Samath et al.
Joint Author
March 2024
JOURNAL PAPER
International
Comprehensive amino acid composition analysis of seed storage proteins of cereals and legumes: identification and understanding of intrinsically disordered and allergenic peptides Journal of Biomolecular Structure and Dynamics Pratibha Sharma, Lakshay Malhotra & Rajinder K. Dhamija
Joint Author
January 2024
JOURNAL PAPER
International
Flavonoids as potential reactivators of structural mutation p53Y220C by computational and cell-based studies Journal of Biomolecular Structure and Dynamics Lakshay Malhotra, Punit Kaur & Abdul Samath Ethayathulla
First Author
August 2023
JOURNAL PAPER
International
Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression Journal of Translational Medicine Ravi Chauhan, Ashna Gupta, Lakshay Malhotra, Ajaz A. Bhat, Raj K. Pandita, Tariq Masoodi, et al.
Joint Author
April 2023
CONFERENCE PAPER/ PROCEEDINGS
International
Ubiquitin Specific Peptidase 37promotes Osteosarcoma oncogenesis by interacting with PCNA and impacting constitutive replication fork movement. Cancer Research Ravi Chauhan; Lakshay Malhotra; Ashna Gupta; Ajaz Bhat; Gunjan Dagar; Tariq Masoodi; Muzafar A. Macha; Ethayathulla Abdul Samath et al.
Joint Author
April 2023
JOURNAL PAPER
International
Putative interactions between transthyretin and endosulfan II and its relevance in breast cancer International Journal of Biological Macromolecules Saurabh Sharma, Lakshay Malhotra, Paromita Mukherjee, Navneet Kaur, Thammineni Krishanlata, Chittur V. Srikanth, Vandana Mishra, Basu Dev Banerjee, Abdul Samath Ethayathulla, Radhey Shyam Sharma
Joint Author
February 2023
JOURNAL PAPER
International
Mechanism of apoptosis activation by Curcumin rescued mutant p53Y220C in human pancreatic cancer Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Lakshay Malhotra, Saurabh Sharma, Gururao Hariprasad, Renu Dhingra, Vandana Mishra, Radhey S. Sharma, Punit Kaur, Abdul S. Ethayathulla
First Author
August 2022
JOURNAL PAPER
International
Comprehensive omics studies of p53 mutants in human cancer Briefings in Functional Genomics Lakshay Malhotra , Alankrita Singh , Punit Kaur , Abdul S Ethayathulla
First Author
July 2022
JOURNAL PAPER
International
Genistein: A novel inhibitor of IL-6/IL-6R interface of the Interleukin-6–mediated STAT3 dependent pathway of carcinogenesis Journal of Molecular Structure Saurabh Sharma, Lakshay Malhotra, Prakarsh Yadav, Vandana Mishra, Radhey Shyam Sharma, Ethayathulla Abdul Samath
Joint Author
February 2021
JOURNAL PAPER
International
Heteroarene-fused anthraquinone derivatives as potential modulators for human aurora kinase B Biochimie Mandeep Singh, Lakshay Malhotra, Md Anzarul Haque, Mukesh Kumar, Alexander Tikhomirov, Valeria Litvinova, Alexander M. Korolev, A.S. Ethayathulla, Uddipan Das, Andrey E. Shchekotikhin, Punit Kaur
Joint Author
January 2021
JOURNAL PAPER
International
Curcumin rescue p53Y220C in BxPC-3 pancreatic adenocarcinomas cell line: Evidence-based on computational, biophysical, and in vivo studies Biochimica et Biophysica Acta (BBA) - General Subjects Lakshay Malhotra, Harsh K.V. Goyal, Sunita Jhuria, Kapil Dev, Saroj Kumar, Manoj Kumar, Punit Kaur, Abdul S. Ethayathulla
First Author
December 2020
Research Projects

No research projects published.

Books

No books published.

Faculty Achievements
YearCategoryRoleLevelName / EventDate From – ToAttachment
2025 REFRESHER COURSE ATTENDED PARTICIPANT National Online Refresher Course (Multidisciplinary/Interdisciplinary Course) on the theme “Mental Health & Wellbeing in Higher Education Institutions: A Step Towards Viksit Bharat” 10.Mar.2025 – 24.Mar.2025
2025 FACULTY DEVELOPMENT PROGRAM ATTENDED PARTICIPANT National One-Week Online National Faculty Development Program on "CANCER AWARENESS FOR COMMUNITY ENGAGEMENT @NEP 2020" 11.Feb.2025 – 18.Feb.2025
2023 FACULTY INDUCTION PROGRAM ATTENDED PARTICIPANT National 4-Week Faculty Induction/Orientation Programme for “Faculty in Universities/Colleges/Institutes of Higher Education” 23.Apr.2023 – 22.May.2023